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University of Oxford signs RFEL for initial signal processing study contract for …

The University of Oxford, a member of the Low Frequency Aperture Array (LFAA) consortium, working together with the Square Kilometre Array (SKA) Organisation…

Finding ways to detect and treat Alzheimer's disease

Alzheimer's disease has long been marked by progress — but not the kind of progress the medical community seeks. It is the most common form of dementia among…

Scientists call for new stewardship of the deep ocean: Earth's last frontier

The deep ocean, the largest domain for life on earth, is also its least explored environment. Humans are now encroaching more vigorously than ever into the…

Immunologists from the University of Bonn topple dogma

To date, immunologists have assumed that the macrophages functioning as “scavenger cells” can be classified into two different forms. In an extensive search,…

Short N terminus Split Inteins – Novel Split Inteins for protein semisynthesis and protein coupling

Protein trans-splicing catalyzed by split inteins is a powerful technique for Assembling a polypeptide backbone from two separate parts. As shown in the figure, the N and C terminal intein fragments associate and fold into the active domain thereby linking the
flanking sequences with a peptide bond. However, split inteins with robust efficiencies and short fragments suitable for Peptide synthesis are rare and have mostly been artificially created exhibiting poor to moderate coupling efficiencies only.

A global map of Jupiter’s biggest moon

Scientists, including Brown University geologists and students, have completed the first global geological map of Ganymede, Jupiter’s largest moon and the…

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