Studies and Analyses

Results of a study in this week’s issue of THE LANCET highlight how improved treatment and management of risk factors have reduced the incidence of stroke by 40% in a region of the UK over the past 20 years.

Stroke is the second largest cause of death worldwide, the largest cause of long-term neurological disability, and the single most costly condition for the UK National Health Service and social services. The rise in the elderly population would be expected to increase the incidence of a

Reduction is significant enough that it might lead to a reduction in the risk of heart disease caused by testosterone suppression

A small adhesive estrogen patch worn by men being treated for advanced prostate cancer lowers cholesterol, according to a new study conducted by Oregon Health & Science University Cancer Institute researchers.

This is important because men who have advanced prostate cancer are often treated with hormone deprivation therapy, which turns off testos

Tactile input has a greater impact on visual perception than we thought

When vision alone can’t tell you what’s going on in your environment, touch can lend a helping hand. A recent study from Vanderbilt University looked at the way this works by forcing people to feel out a visually ambiguous situation.

Researchers Randolph Blake, Kenith V. Sobel and Thomas W. James created such a scenario by asking subjects to describe the rotation of a virtual sphere with an ind

Findings may explain mood and behavior changes in women

Medroxyprogesterone acetate (MPA), a synthetic form of the naturally occurring steroid hormone progesterone widely used in contraceptives and hormone replacement therapy (HRT), increases aggression and anxiety and reduces sexual activity in female monkeys, according to a study published in the June edition of The Journal of Clinical Endocrinology and Metabolism. The investigators, from the Yerkes National Primate Research Center

Survival, toxicity greater in Japanese patients, “common arm” analysis shows

A chemotherapy regimen commonly used to treat non-small cell lung cancer is both more effective and more toxic in Japanese patients than in American patients, researchers reported Saturday at the annual meeting of the American Society of Clinical Oncologists. The first of its kind, this analysis underscores the importance of genetic variations in medicine and points to a need for increased international colla

One of the most common challenges facing oncologists today is determining the best course of treatment for their patients – one that would be effective and have the fewest possible side effects. In a study presented today at the 40th Annual Meeting of the American Society of Clinical Oncology in New Orleans, Fox Chase Cancer Center researchers have identified genetic markers in the blood that can help predict a patient’s response to and side effects from irinotecan, a common chemotherapy drug fo