Biosynthesis of N-Acetylneuraminic acid {NeuNAc, NANA) from the renewable ressource chitin using Trichoderma reesei as whole-cell biocatalyst

NeuNAc is used as a precursor for the production of neuraminidase inhibitors, which are used for the treatment of viral diseases. {e.g. drug Relenza). A new process was developed at the TU Vienna combining the advantage of a single-step process and using the cheap and renewable substrate chitin.

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