CCL17 AS CENTRAL IMMUNE REGULATOR – CCL17 INHIBITORS FOR USE IN T HELPER CELL-DRIVEN DISEASES
The current invention is based on the identification of the role of CCL17 in the genesis of T helper cell Th1-driven diseases, in particular atherosclerosis and autoimmune diseases.
The invention provides novel therapeutic approaches for treating atherosclerosis and other diseases such as myocardial infarction, stroke, peripheral vascular disease, chronic kidney disease and angina pectoris. These approaches are based on interfering with the interaction between the CCL17-cytokine and the CCL17-receptor. Respective agents will also be beneficial for the treatment of autoimmune diseases e.g. hypersensitivity dermatitis (CHS), psoriasis, rheumatoid arthritis, Bechterew's disease and inflammatory bowel disease (Crohn`s disease).
Further Information: PDF
PROvendis GmbH
Phone: +49 (0)208/94105 10
Contact
Dipl.-Ing. Alfred Schillert
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Pinpointing hydrogen isotopes in titanium hydride nanofilms
Although it is the smallest and lightest atom, hydrogen can have a big impact by infiltrating other materials and affecting their properties, such as superconductivity and metal-insulator-transitions. Now, researchers from…
A new way of entangling light and sound
For a wide variety of emerging quantum technologies, such as secure quantum communications and quantum computing, quantum entanglement is a prerequisite. Scientists at the Max-Planck-Institute for the Science of Light…
Telescope for NASA’s Roman Mission complete, delivered to Goddard
NASA’s Nancy Grace Roman Space Telescope is one giant step closer to unlocking the mysteries of the universe. The mission has now received its final major delivery: the Optical Telescope…