Fluorine-substituted Amphetamine Derivatives against Parkinson’s Disease

We present new fluorinated amphetamine derivatives, that exert their positive effect not only via the “classic”, well-known dopaminergic system but more pronounced in the serotonergic system: Our primary investigations revealed a significant role as agonists at the serotonin-5-HT(1A)-receptor combined with affinity at the serotonine transporter (SERT).

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Eberhard Karls Universität Tübingen
Phone: +49 (7071) 29-72639

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Dr. Rolf Hecker

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