Method for the Diastereoselective Synthesis of Pronucleotides

<b>UHH052/05.04.2011</b><br><br>

The present invention is directed to a process for the diastereoselective synthesis of phosphorus compounds, particularly pronucleotides (nucleotide prodrugs). Pronucleotides represent a promising alternative to improve the biological activity of nucleoside analogs in antiviral and cancer chemotherapy.

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