New Wnt Targeting and Apoptosis Inducing Lead-Compound for Cancer Treatment
The Wnt signaling pathway plays an important role in the regulation of cell proliferation and differentiation. Aberrant activation of the Wnt signaling pathway is known to promote uncontrolled cell growth and survival. Compound library screening and med-chem based structure activity improvement revealed potent Wnt signaling inhibitors that selectively affected carcinoma cell lines. In addition, further experiments proved these compounds to induce apoptosis.
Further information: PDF
DKFZ (German Cancer Research Center, Deutsches Krebsforschungszentrum)
Phone: +49-6221-42 2955
Contact
Dr. Ruth Herzog
As Germany's association of technology- and patenttransfer agencies TechnologieAllianz e.V. is offering businesses access to the entire range of innovative research results of almost all German universities and numerous non-university research institutions. More than 2000 technology offers of 14 branches are beeing made accessable to businesses in order to assure your advance on the market. At www.technologieallianz.de a free, fast and non-bureaucratic access to all further offers of the German research landscape is offered to our members aiming to sucessfully transfer technologies.
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Tackling Life-Threatening Fungal Infections Using RNA Modifications
Importance of RNA modifications for the development of resistance in fungi raises hope for more effective treatment of fungal infections. An often-overlooked mechanism of gene regulation may be involved in…
Unraveling Aphasia: Global Study Breaks Down Patients’ Struggle with Verb Tenses
An international team of researchers, including scientists from the HSE Centre for Language and Brain, has identified the causes of impairments in expressing grammatical tense in people with aphasia. They discovered…
Facing the Storm: A Prepped Up Future Against Extreme Climatic and Weather Changes
From the persistent droughts of southern Africa and Central America in the early part of the year to the more recent devastating extreme rainfall in Spain and the deadly Hurricane…