Nucleoli disorganisation by knocking down specific Alu-repeat containing RNA sequences
The assembly and maintenance of functional nucleoli is essential for cell viability. DKFZ researchers developed anti-sense oligos that target Alu element-containing RNAs, which are essential for intact nucleoli, for cancer cell specific induction of apoptosis.
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DKFZ (German Cancer Research Center, Deutsches Krebsforschungszentrum)
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