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In commercially available piezoelectric nebulizers, the properties of the generated aerosols are largely predefined by the design of the nebulizer device. Particle size distribution and output can hardly be varied and it is often only inadequately possible to generate a sufficiently large fraction of fine particles for pulmonary deposition.
Aerodynamic properties and the mass flow of the generated aerosols can however be influenced without changing the piezoelectric nebulizer device by an addition of modified polymers.
Objective of this innovation is a coating of nebulizer membranes that is aimed at an improvement of the aerosol physical parameters of the aerosol which is generated. This is achieved by reducing the hole diameter of the coated membrane used.
This innovation concerns biocompatible polymeric nano-, meso- and micro-polymer particles which are able to bind pathogenic proteins that penetrate into the lining layer of the lung. These particles can be used for the prevention and treatment of lung diseases which are associated with an increased lung surface tension and a damage of the pulmonary surfactant.
Diamondoids are molecules whose framework structure represents a section of the diamond lattice. Due to their size in the range of 0.5 ? 2 nm, they can be considered as ?nano diamonds? with a hydrogen-terminated surface. Despite their small size, they comprise several properties which are characteristic for diamonds, such as a negative electron affinity and, in particular, chemical inertness.
The test procedure demonstrates the efficacy of substances and/or methods which eliminate infectivity using several quantitative measurement parameters (HBsAg, HBeAg, mRNA, cccDNA) for the detection of HBV infection after a titer reduction by more than 4 log 10 steps and is, thus, the first HBV infectivity test to meet the new guidelines of the Robert Koch Institute (RKI) and the German Association for the Control of Virus Diseases (DVV) for the efficacy of disinfectants and virus-inactivating procedures.
Simultaneous insights into the micro dynamics and nano functionality of biological samples can be facilitated via correlative light and electron microscopy (CLEM). Scientists from Goethe University Frankfurt am Main developed novel software CLEM. It allows for the automated and efficient correlation of light- and electron-microscopic images from any two light and electron microscopes of choice with a precision of up to 25 nm.