Domain-exchanged complete antibody composed of the Fc fragment and variable domains where CH1 and CL domains have been exchanged for a pair of CH3 domains.
Modular immunoglobulins composed of Fab-like fragment with HerceptinVL and VH region and CH3 domains and an unmodified Fc fragment are described. Novel is an increased binding to FcR³III, which leads to potentiated T-cell activation upon binding to a Her2-positive cell line
A new aluminum based photo acid generator which is easy to synthesize[2, 3] (sulphonium as weil as iodonium salt) at high yields is described. The educts are inexpensive and commercially available. This high stability and the abandonment of any heavy metals in our novel PAG prompts a low toxicity.
Die Erfindung dient zur Verhinderung von Tauwasserbildung an den Tramköpfen einer Holzbalkendecke bei Innendämmung. Die Wärmeleitbleche ermöglichen eine energiesparende Temperierung des Tramkopfs und somit eine dauerhafte Sanierung und Erhaltung der Tramdecke.
The invention prevents the condensation of water forming on the traverse heads of a wooden beam ceiling when the building is insulated internally. Using heat conduction plates enables energy-saving temperature control of the beam head area and thus durable renovation of a wooden beam ceiling.
The new type of solar cells contains copper oxide phases as a photovoltaic absorber film in combination with e.g. AlGaN, ZnMgO, or ZnBeO thin film. These are non-toxic and their production is possible in industrial scale (e.g. using the cathode sputtering technique) and with low energy consumption.
Food-borne salmonella infections are mostly arising from poultry or pigs. While actions have been taken for poultry there has only been minor success for a pig vaccine. Scientists at the University of Veterinary Medicine Hanover developed a marker vaccine for pigs, which allows differentiation of vaccinated and infected animals.