Technology Offerings

Scientists of the University of Duisburg-Essen developed a platform, which facilitates the detection of deletions and insertions as well as point mutations in target genes from a variety of sources against a huge background of wild type alleles, making a clear “Yes” or “No” output possible and thereby simplifying therapeutic decisions.
Neither expensive and complicated equipment nor specialized personnel is needed. The assay is robust and applicable in all laboratories equipped with an RT-PCR machine. It can easily be established for point of care (PoC) purposes.
This sensitive technology now enables clinicians to be independent of the scarce resource “tissue biopsy”. By using blood (ctDNA, cfDNA or CTC) it opens new non-invasive possibilities for monitoring the mutation status of patients before and during treatment as well as to detect disease relapse early. A European and a US patent have already been granted, other applications are pending.

Invention is used for additive manufactur-ing of parts out of amorphous or partly crystalline metals with low melting point. This is done with an extrusion method. The used material, metal granulate, is heated up to the glass transition temperature and partly up to the melting temperature. By doing so, the material is moved into a thermoplastic state. After heating, the material can then be extruded by pressure and is selectively placed onto a building platform. The system described in this invention is able to manufacture hollow constructions along with complex parts, all with good mechanical properties. Due to the generating of the part onto the building platform it is not necessary to clean or post process the part as it would be with other methods.

Advances in neurosciences are linked to neuron stimulation. Our technology presents the use of Schottky miniaturized photovoltaic cells for this goal, showing remarkable advantages respect stablished techniques, as Patch clamp or Optogenetics.

When producing rear contact solar cells, both negatively and positively doped areas need to be produced on the rear of the solar cell. Moreover, the front side of the solar cell has to be sufficiently passivated in order to minimize surface recombination. This means three differently doped areas are required.
Scientists of the University of Konstanz have now developed a new method for producing these three areas in a single diffusion step. This approach is based on the application of a borosilicate glass layer and partial silicon nitride masking on the rear of the solar cell.

Scientists at the University of Stuttgart have developed an absorption chiller that is extremely compact, lightweight and stable in terms of operation, even at low evaporator temperatures and high heat rejection temperatures. Because of its compactness the absorption chiller has lower production costs and requires less refrigerant than conventional absorption chillers.

The invention discloses two chemical compound families derived from tetrahydrotriazine or coumarin selectively targeting the autophagic pathway.