Technology Offerings

IAP – Intrinsic Antimicrobial Polymers

State of the art antimicrobial polymers are polymers with antimicrobial additives such as silver or copper. Additionally, a further approach is using functionalized monomers, containing amine or quaternary ammonium/phosphonium groups. These monomers can be polymerized to intrinsically microbial polymers. Unfortunately, they suffer from poor material properties (low glass transition temperature, high water uptake).
The novel intrinsic antimicrobial polymers overcome these shortcomings. Several groups of polymers have been developed (homopolymers and copolymers) with favorable processing characteristics, e.q. can be used in an injection molding process or press molding.
The standard JIS Z 2801 test to quantitatively test the ability to inhibit the growth of microorganisms over a 24 hour period of contact reveals a reduction of up to log 7,1.
Four patent applications have been filed at the European Patent Office. Further international applications are still possible. On behalf of the Fachhochschule Münster PROvendis offers licenses for interested enterprises.

Metallized open-cell foams and fibrous substrates

Open-cell foams and fibrous substrates provide a wide range of properties which make them very attractive for different applications in many fields. Metallization of open-cell foams and fibrous substrates could give novel polymer / metal composites with highly interesting properties for a variety of ap- plications. However, the applications with metal composites are still limited, because of the existing problems due to the metallization methods, where often complex or laborious procedures are required or are restricted to certain polymer surfaces, if high quality metallization is desired.
Therefore, there is a need for the homogenous metallization of open-cell mel- amine formaldehyde (MF) foams which provides electrically conductive foams with a specific resistance R < 50 Ω mm2 m–1, which until now is not known in the current state-of-the-art.

Marbostat

Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that leads to progressive joint deformity, disability, and occasionally premature death. Emerging evidence suggests the utility of histone deacetylase inhibitors (HDACi) in the treatment of chronic immune and inflammatory disorders such as rheumatoid arthritis. Several studies have shown the decreasing effect of selective HDAC6 inhibitors on the secretion of pro-inflammatory cytokines in vitro and a significant therapeutic response has been demonstrated in animal inflammatory disease models.

Food Quality Control – Culture medium for yeasts with high osmotic tolerance

Food industry is seeking for strategies to enhance production throughput in order to reduce costs. One bottleneck is not the production process itself, but the subsequent quality control analysis of each production charge. The herein described invention expedites this process and is therefore of interest for contract analytic labs as well as for food production companies with an own quality analysis laboratory. The culture medium has been optimized for osmo-tolerant yeast growth and has been tested and validated in comparison to conventional culture media. The invention is ready for industrial use.
On behalf of the University of Applied Sciences Ostwestfalen-Lippe, PROvendis offers access to rights for commercial use as well as the opportunity for further co-development. In case of interest we will be pleased to inform you about the patent status.

Multiphase Loop Reactor – New architecture for a bioreactor

The herein presented new architecture of a bioreactor basically consists of an inner and outer cylinder, whereas the disperse phases are added in either one of the cylinders. The two key elements of the design are baffles on the upper end of the inner cylinder, which prevent a mixture of the disperse phases, in combination with a collection device placed on top of the inner cylinder. This design allows continuous product extraction by means of biocompatible solvents and a simultaneous oxygen supply.
Moreover, the addition of both disperse phases and the regulation of the loop flow can be adapted continuously and anytime through steering of the volume flow rates. With this invention three or four phases can be brought together intensively with only small transport hindrances while the two additional disperse phases are spatially separated. On behalf of the University of Aachen (RWTH Aachen), PROvendis offers access to rights for commercial use as well as the opportunity for further co-development and evaluation. The design of the reactor and the requested fluid dynamics can be assisted by the inventors.

Light-emitting electrochemical cells

We present light-emitting electrochemical cells based on hybrid lead halide perovskite nanoparticles. The latter are not oxygen sensitive and therefore the LEECs can be produced from solution or by spraying. The resulting LEECs are characterized by a four layer structure. They feature moderate luminance (> 2 cd/m2) and efficacies (> 0.02 cd/A), but high stabilities even after keeping
the devices under ambient conditions.

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