Technology Offerings

Autocorrelation-Based Detection of Infinite Loops at Runtime

We present a new algorithm for the detection of infinite loop bugs in software. Source code is not needed. The algorithm is based on autocorrelation of a program execution’s branch target address sequence. We describe the implementation of the algorithm in a dynamic binary instrumentation tool; the result is light-weight enough to be applied continuously at runtime. Functionality of the tool is
evaluated with infinite loop bug test cases from the Juliet test suite for program analyzers. Applicability of the algorithm to production software is demonstrated by using the tool to detect previously known infinite loop bugs in cgit, Avahi and PHP.

Phase-separation cell 2: Liquid/liquid dispersion, reaction and separation processes in centrifugal field in one device as one closed batch process

The dispersion and reaction of two immiscible liquids with subsequently separation of the products according to the state of the art need several steps. The invention enables process intensification, the dispersion, reaction and separation of two immiscible liquids in one device in one batch process. The core of the invention is a rotatable reactor with an integrated centrifuge. Thus the invention enables equipment reduction of separate mixing and separation devices. Depending on how the motors run towards another, a mixing or a centrifugal effect is produced. Competitive Advantages:
•Compact and cost effective
•Mixing and Separation in one device
•Complete control on measurements parameters
•Variable energy input
•Quantitative results
•Short contact times also with coalescence inhibited substance Systems
•No back-mixing

Current Status: A patent application for this invention has been filed in Germany. On behalf of the RWTH University, PROvendis is seeking a partner for further development in view of licensing the Technology.

Phase-separation cell 1: Measurement equipment for liquid/liquid dispersion and separation processes in centrifugal field

The characterization of sedimentation and coalescence processes in a multi-phase system is a crucial step for the design and development of equipments for phase dispersion and separations. An established model of phase separator is based on the application of a gravitational field on the multiphase system. For those kinds of equipments, an early system characterization is possible thanks to suitable procedures and instruments established at laboratory-scale.

An effective alternative to gravitational separators are annular centrifugal contactors. Those equipments offer a better scalability and flexibility respect to the gravitational separator. Furthermore, they provide a versatile solution as phase separators as well as chemical reactors. Although centrifugal contactors are already established at the industrial level, a pre-characterization of the systems of interest in small equipment is not possible with the existing technologies. Competitive Advantages:
•Compact and cost effective
•Enables pre-characterization al lab level for processes in centrifugal contactors
•On-line camera
•Complete control on measurements parameters
•Quantitative results

Current Status: A patent application for this invention has been filed in Germany. On behalf of the RWTH University, PROvendis is seeking a partner for further development in view of licensing the technology.

Plasma cushion for treating objects

Device and method of treating objects & bulk materials with a physical plasma cushion at atmospheric pressure. The plasma passes from the discharge chamber to the treatment chamber through a sparger plate comprising a multitude of holes, producing a plasma cushion, which supports & slides/pushes the objects while treating them.

Surgical Device for Real-Time Elastography

Mechanical elasticity is a central parameter of living cells and tissues. Cancerous and healthy tissues, for example, have a different elasticity. Therefore, tools are under development to make tissue elasticity a new diagnostic marker in medicine1. Nevertheless, these efforts have been hampered by poor spatial resolution (i.e. ultrasound elastography) or by their usability being restricted to an in vitro environment (i.e. scanning ion conductance microscopy2,3,4 (SICM)).
Here, we present a novel instrument which transfers principles of SICM into the macro-environment of endoscopy or laparoscopy. This opens the door for a real-time measurement of tissue elasticity, e. g., during minimally invasive surgery.
Our handheld device uses the pressure of a water jet for inducing a deformation of the outer surface of any given tissue. The resulting change in a simultaneously recorded ion current between two electrodes on the “water nozzle” renders charac-teristic parameters for the elasticity of the tissue.

A novel method for enhanced detection of hemolytic activity of gram-positive pathogenic microorganisms

Many Gram-positive bacteria such as are significant pathogens of both animals and humans. Reliable detection of hemolytic activity is a cornerstone for diagnosis of the pathogenic properties of these bacteria.
Here an improved diagnostic test that enables reliable detection of pathogenic Gram-positive bacteria by enhancing hemolytic zones on blood agar plates is presented.

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