Technology Offerings

Electrical sensing array for the detection of multiple biological or chemical species in complex samples with applications e.g. in chemical analysis and medical diagnostics.
Such a device allows for simultaneous and spatiotemporal detection of concentration gradients in test samples. A direct integration of the proposed sensor array into many kinds of sensing platforms like microfluidics or lab-on-a-chip systems is possible and a combination with conventional optical read-out techniques can be realized.

Itaconic acid (ITA) – also known as methylenesuccinic acid or butanedioic acid – is one of the top 12 bio-based chemical building blocks and thus a promising platform compound for production of biofuels, chemical compounds, including e.g. detergents, and polymers, including plastics and artificial glass.
Itaconic acid (C5H6O4) is an organic dicarbonic acid which is soluble in water, ethanol, and acetone.
The new method for production of itaconic acid uses genes encoding for the itaconic acid biosynthesis pathway of the genus Ustilago maydis.

Invention of a stretcher on wheels for rescuing persons on big events with increased ease of operation for the rescue staff. The retractable cover protects the patient from rain and looks of bystanders.

Temperaturstabilisierung ist bei hochauflösenden Mikroskopen sehr wichtig. Die von DKFZ entwickelte Technologie ermöglicht mit Durchstrom von exakt temperierter Flüssigkeit durch die Temperiereinheiten die genaue Regulation der Temperatur und somit eine Wärmeaufnahme und -abgabe am Mikroskopaufbau.

Future electro-mobility concepts require advanced battery technologies. Main drawbacks today are restrictions in energy density, cycling stability, and cost. The presented invention provides a solution that helps to overcome these problems. Extensive laboratory tests have already demonstrated the advantages of the invented process for preparing lithium-ion battery electrodes. Further improvement is currently under development. PROvendis offers licenses for this invention to interested companies on behalf of the University of Muenster, Germany.

Perfusion analysis in animal models (e.g. myocardial infarction) is currently determined by using fluorescent particles or dyes that are injected into circulation. They distribute throughout all blood vessels and stain them permanently. Thus it is possible to distinguish areas that are supplied with blood and those that are not. Since the dyes are long-lasting in the tissues they interfere with subsequent methods of analysis. A model animal that is used for perfusion analytics can therefore only be used for this specific analytical method.
The present invention overcomes these drawbacks by injecting non fluorescent inert particles that are the first component of an orthogonal system. After perfusion with these particles, the second component is added to frozen tissue sections of interest. Thus, perfusion analysis is solely performed on a selected tissue section, without any limitations for the remaining tissue.
This approach allows a background-free subsequent tissue analysis, optimizes data harvest, is economic and reduces animal consumption.