The inventors here present a novel, highly specialized plasma membrane protein responsible for citrate uptake in cancer cells. This transporter with its function of citrate import is a specific marker for cancer cells and offers therefore a promising target for diagnostic and therapeutic approaches.
The invention provides small molecular compounds as potential drugs against trypanosome infection diseases including African trypanosomiasis (human “sleeping sickness and cattle “Nagana pest”), Chagas disease and Leishmaniasis.
The section food process engineering at the Karlsruhe Institute of Technology (KIT) has developed a processing concept and the required homogenization valve to produce dispersions of solid particles with reproducible and uniform characteristics without the use of special additives (emulsifiers or protective colloids). The particle size can be adjusted within a broad range, with the possibility of even submicron-sized particles. Particles generated by this process are of particular use in paints, varnishes and pharmaceuticals.
An innovative, energy-saving heat forming method has been developed at the University of Stuttgart for the fabrication of thermoplastic molded parts, in particular fibre-reinforced composites from semi-finished products (organic sheets). The method provides a more effective and surface-preserving way of heating and forming semi-finished products. In addition, it is possible to achieve a process-integrated quality assurance, a documentation of the quality as well as an individual quality assessment.
At the University of Stuttgart (Germany) a new method was developed to significantly improve the stability of laminar flow over e.g. a wing, tail plane or wind turbine rotor in order to reduce drag and therefore reach higher efficiency of machines.
The novel measurement system permits minimally invasive measurements of tracer LIF-signals by a combination of fibre and microoptical elements integrated into a fully functional spark plug. Thus e.g. fuel distribution, temperature or air-fuel ratio can be measured.