Technology Offerings

Scientists at the University of Stuttgart developed a new process for confocal transmission microscopy, which permits measuring moving phase objects. The process is ideal for the determination of optical thickness and depth position of living cells or chromosomes. For transparent and opaque micro particles it is possible to determine the spatial distribution and the lateral dimensions quantitatively.

Reading up to 100 superimposed layers in an optical storage volume simultaneously offers a very high data transfer rate such as is needed for example in databases or data storage. Modified DVDs can be used as data storage media.

At present only the symptoms of the hereditary disease CF, which results in death at a young age, are being treated, not the actual cause. The novel preventive therapeutic strategy consists of an early treatment of CF before any disease-specific symptoms can be detected. In animal trials the early therapy with sodium channel blocker amiloride, commencing immediately after birth, prevents the development of CF. Clinical trials of amiloride as an early intervention preventive therapy against CF are already in the planning phase.

The multiresistant hospital microbe Pseudomonas aeruginosa can form protective biofilms, which make its treatment significantly more difficult. Chronic infections, such as urinary tract infections, enterocolitis, and meningitis, can be fatal, particularly for patients with a depressed immune system. The present invention consists of compounds with high specificity and high affinity which are based on the natural ligand Mannose and act against the lectin LecB, which is a component of the biofilm. This opens the opportunity for a more effective antibiotics therapy by inhibiting the formation of the biofilm through the application of these new glycomimetics.

An innovative procedure has been developed to control induction heating of material used for semi-solid metal casting. By analyzing electrical value and permeability of the material the grain structure can be determined during the heating process. The induction heating can be regulated accordingly so that the material retains the optimal grain structure for forming.

The invention offers a method for generation of reproducible secret keys in products which were manufactured by means of lithographic production processes, such as chips.