Prevention of Graft versus Host Disease

Graft versus Host Disease (GVHD) is one of the major complications associated with transplantation. It is caused by donor T cells, which recognize the genetically dissimilar recipient and therefore attack the host’s body cells. At present there is no effective therapy available. We offer a simple method, whereby the transplant once is treated ex vivo with a well known substance prior to transplantation. For that only a very low concentration of the substance and a short incubation time are used. Remarkably, GVHD is reduced significantly. Due to the ex vivo treatment no side effects are expected.

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