Single-chain fragments against non-coat proteins of plant viruses for viral disease control in plant

Virus diseases of plants cannot be treated in a curative way, the best strategy to construct and obtain healthy plants is to establish a virus resistant genotype. Here conventional cultivation reaches limits and genetically induced resistance was up to now limited to one virus and its near relatives.

These newly developed single chain Fv fragments (scFv) which are targeted against a conserved domain in a plant viral RNA-dependent RNA polymerase (RdRp) enable a broad and efficient control of viral diseases in plants.

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