Monoclonal antibodies: Anti-mouse Chemokine Receptor 7 (CCR7) mAb
Scientists at the Georg-August-University produced a monoclonal antibody which recognises murine CD197, a 43kD member of the G coupled receptor family, which is commonly known as chemokine receptor 7 (CCR7). In mice, CD197 is expressed on most naive T cells, a subset of memory T cells, B cells, mature dendritic cells, NK cells and CD34+ macrophage progenitor cells. CD197 is a functional receptor for chemokines CCL19 and CCL21. The receptor plays an important role in regulating the trafficking and homing of lymphocytes and dendritic cells to secondary lymphoid organs. Clone 4B12 does not block the binding of the ligand to CD197.
Further Information: PDF
MBM ScienceBridge GmbH
Phone: (0551) 30724-151
Contact
Dr. Jens-Peter Horst
Media Contact
All latest news from the category: Technology Offerings
Newest articles
Magnetic Effect: Groundbreaking Discovery for Low-Temperature Thermoelectric Cooling
Researchers at the Max Planck Institute for Chemical Physics of Solids, in collaboration with Chongqing University and the Max Planck Institute of Microstructure Physics, have achieved a breakthrough in topological…
Parallel Paths: Understanding Malaria Resistance in Chimpanzees and Humans
The closest relatives of humans adapt genetically to habitats and infections Survival of the Fittest: Genetic Adaptations Uncovered in Chimpanzees Görlitz, 10.01.2025. Chimpanzees have genetic adaptations that help them survive…
You are What You Eat—Stanford Study Links Fiber to Anti-Cancer Gene Modulation
The Fiber Gap: A Growing Concern in American Diets Fiber is well known to be an important part of a healthy diet, yet less than 10% of Americans eat the minimum recommended…